Notice Of A Change In The Percentage Level Of A Substantial Shareholder's Interest

Part I
1.	Date of notice to issuer	02/05/2008
2.	Name of Substantial Shareholder	UBS AG
3.	Notice Type	Notice of a Change in the Percentage Level of a Substantial Shareholder's Interest or Cessation of Interest.
Part II - Not Required
Part III
1.	Date of change of Interest	01/05/2008
2.	The change in the percentage level	From 4.67 % To 4.20 %
3.	Circumstance(s) giving rise to the interest or change in interest	# Others THE CHANGE IS A RESULT OF THE FOLLOWING: (1) DECREASE IN UNITS IN BIO-TREAT TECHNOLOGY RECEIVED AS COLLATERAL WHICH CARRY VOTING RIGHTS, PARTIALLY OFFSET BY; (2) INCREASE IN POSITIONS HELD ON BEHALF OF PRIME BROKERAGE CLIENTS
4.	A statement of whether the change in the percentage level is the result of a transaction or a series of transactions:	A SERIES OF TRANSACTIONS
Part IV
1.	Holdings of Substantial Shareholder, including direct and deemed interest :
	Direct Deemed No. of shares held before the change 4,813,640 41,633,683 As a percentage of issued share capital 0.54 % 4.67 % No. of shares held after the change 4,813,640 37,442,664 As a percentage of issued share capital 0.54 % 4.20 %