Notice Of A Substantial Shareholder's Interest

Part I
1.	Date of notice to issuer	29/04/2008
2.	Name of Substantial Shareholder	UBS AG
3.	Notice Type	Notice of a New Substantial Shareholder's interest.
Part II
1.	Date of change of Interest	25/04/2008
2.	Name of Registered Holder	UBS AG
3.	Circumstance(s) giving rise to the interest or change in interest	# Others (1) INCREASE IN SHARES IN BIO-TREAT TECHNOLOGY LIMITED RECEIVED AS COLLATERAL;THESE SHARES CARRY VOTING RIGHTS (2) INCREASE IN POSITIONS HELD ON BEHALF OF PRIME BROKERAGE CLIENTS.
4.	Information relating to shares held in the name of the Registered Holder
	No. of Shares held before the change 39,934,741 As a percentage of issued share capital 4.48 % No. of Shares which are subject of this notice 5,019,582 As a percentage of issued share capital 0.56 % Amount of consideration (excluding brokerage and stamp duties) per share paid or received 0.335 No. of Shares held after the change 44,954,323 As a percentage of issued share capital 5.04 %
Part III - Not Required
Part IV
1.	Holdings of Substantial Shareholder, including direct and deemed interest :
	Direct Deemed No. of shares held before the change 4,813,640 35,121,101 As a percentage of issued share capital 0.54 % 3.94 % No. of shares held after the change 4,813,640 40,140,683 As a percentage of issued share capital 0.54 % 4.50 %