Notice Of A Substantial Shareholder's Interest

Part I
1.	Date of notice to issuer	04/06/2008
2.	Name of Substantial Shareholder	UBS AG
3.	Notice Type	Notice of a New Substantial Shareholder's interest.
Part II
1.	Date of change of Interest	02/06/2008
2.	Name of Registered Holder	UBS AG
3.	Circumstance(s) giving rise to the interest or change in interest	# Others (1) INCREASE IN UNITS IN BIO-TREAT TECHNOLOGY LIMITED RECEIVED AS COLLATERAL WHICH CARRY VOTING RIGHTS, (2) INCREASE IN POSITIONS HELD ON BEHALF OF PRIME BROKERAGE CLIENTS, PARTIALLY OFFSET BY, (3) DECREASE IN LOAN INTERNAL, (4) DECREASE IN POSITIONS HELD BY UBS WM USA ON BEHALF OF ITS DISCRETIONARY CLIENTS
4.	Information relating to shares held in the name of the Registered Holder
	No. of Shares held before the change 43,428,323 As a percentage of issued share capital 4.87 % No. of Shares which are subject of this notice 3,230,000 As a percentage of issued share capital 0.36 % Amount of consideration (excluding brokerage and stamp duties) per share paid or received 0 No. of Shares held after the change 46,658,323 As a percentage of issued share capital 5.23 %
Part III - Not Required
Part IV
1.	Holdings of Substantial Shareholder, including direct and deemed interest :
	Direct Deemed No. of shares held before the change 4,813,640 38,614,683 As a percentage of issued share capital 0.54 % 4.33 % No. of shares held after the change 4,813,640 41,844,683 As a percentage of issued share capital 0.54 % 4.69 %