| Part I | |||||||||||||||||
| 1. | Date of notice to issuer | 25/06/2008 | |||||||||||||||
| 2. | Name of Substantial Shareholder | UBS AG | |||||||||||||||
| 3. | Notice Type | Notice of a New Substantial Shareholder's interest. | |||||||||||||||
| Part II | |||||||||||||||||
| 1. | Date of change of Interest | 23/06/2008 | |||||||||||||||
| 2. | Name of Registered Holder | UBS AG | |||||||||||||||
| 3. | Circumstance(s) giving rise to the interest or change in interest |
# Others (1) INCREASE IN SHARES IN BIO-TREAT TECHNOLOGY LIMITED RECEIVED AS COLLATERAL WHICH CARRY VOTING RIGHTS, PARTIALLY OFFSET BY; (2) DECREASE IN LOAN INTERNAL AND (3) DECREASE IN POSITIONS HELD BY UBS WM USA ON BEHALF OF ITS DISCRETIONARY CLIENTS |
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| 4. | Information relating to shares held in the name of the Registered Holder | ||||||||||||||||
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| Part III - Not Required | |||||||||||||||||
| Part IV | |||||||||||||||||
| 1. | Holdings of Substantial Shareholder, including direct and deemed interest : | ||||||||||||||||
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